CU-CPT9b

CAT: 0804-HY-112051-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-112051-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CU-CPT9b is a specific TLR8 antagonist, with an IC50 of 0.7 nM. CU-CPT9b shows high binding affinity towards TLR8 with a Kd of 21 nM[1].
CAS Number
[2162962-69-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/CU-CPT-9b.html
Concentration
10mM
Purity
99.03
Solubility
DMSO : 83.33 mg/mL (ultrasonic)
Smiles
OC1=C(C)C=C(C=C1)C2=CC=NC3=CC(O)=CC=C32
Molecular Formula
C16H13NO2
Molecular Weight
251.28
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhang S, et al. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat Chem Biol. 2018 Jan;14 (1) :58-64.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR8

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