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PRMT5-IN-41

CAT: 0804-HY-163590Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163590Size:1 Each
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Description
PRMT5-IN-41 (compound 130) is a potent and orally active PRMT5 inhibitor. PRMT5-IN-41 inhibits hERG ion channel with IC50 value of 1.36 µM[1].
CAS Number
3034034-32-4
UNSPSC
12352005
Target
Histone Methyltransferase; Potassium Channel
Type
Reference compound
Related Pathways
Epigenetics; Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-in-41.html
Smiles
CN([C@H]1C2=CC=C(C(F)(F)C(F)(F)F)C=C2OC1)C(C3=CC=C4N=C(N)C5=CN=CN5C4=C3)=O
Molecular Formula
C22H16F5N5O2
Molecular Weight
477.39
References & Citations
[1]Bing Yao, et al. Novel prmt5 inhibitor and use thereof. WO2024067433A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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