PRMT5-IN-41

• Description:

  PRMT5-IN-41 (compound 130) is a potent and orally active PRMT5 inhibitor. PRMT5-IN-41 inhibits hERG ion channel with IC50 value of 1.36 µM[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase; Potassium Channel

• Type:

  Reference compound

• Related Pathways:

  Epigenetics; Membrane Transporter/Ion Channel

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-41.html

• Smiles:

  CN([C@H]1C2=CC=C(C(F)(F)C(F)(F)F)C=C2OC1)C(C3=CC=C4N=C(N)C5=CN=CN5C4=C3)=O

• Molecular Formula:

  C22H16F5N5O2

• Molecular Weight:

  477.39

• References & Citations:

  [1]Bing Yao, et al. Novel prmt5 inhibitor and use thereof. WO2024067433A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3034034-32-4