PRMT5-IN-41

• Target:

  Histone Methyltransferase|||Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel|||Chromatin/Epigenetic

• Bioactivity:

  PRMT5-IN-41 (compound 130) is an effective orally active inhibitor of PRMT5. It inhibits the hERG ion channel with an IC50 of 1.36 µM.

• Smiles:

  C(N(C)[C@H]1C=2C(OC1)=CC(C(C(F)(F)F)(F)F)=CC2)(=O)C=3C=C4N5C(C(N)=NC4=CC3)=CN=C5

• Molecular Formula:

  C22H16F5N5O2

• Molecular Weight:

  477.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3034034-32-4