PRMT5-IN-23

CAT: 0804-HY-P3822Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P3822Size:1 Each
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Description
PRMT5-IN-23 (compound 50) is an inhibitor of protein arginine methyltransferase 5 (PRMT5) with anti-tumor activity. PRMT5 is a type of protein arginine methyltransferase, and is a new anti-tumor target related to epigenetic modification[1].
UNSPSC
12352209
Target
Histone Methyltransferase
Type
Peptides
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt5-in-23.html
Solubility
10 mM in DMSO
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(N[C@H](CCCCC[C@@H](C(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(C(O)=O)C(O)=O)C(N[C@H](C(N)=O)CCCCNC(NC2=CC3=C(C4(C5=C(OC6=C4C=CC(O)=C6)C=C(O)C=C5)OC3=O)C=C2)=S)=O)=O)=O)CC(O)=O)=O)NC7=O)C(N[C@@H](CCC(N)=O)C(N[C@H]7CC8=CC=C([N+]([O-])=O)C=C8)=O)=O)=O)=O)C
Molecular Formula
C75H91N15O25S
Molecular Weight
1634.68
References & Citations
[1]Fallot LB, et al. Structure-Activity Studies of 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators. J Med Chem. 2022 Nov 24;65 (22) :15238-15262.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
PRMT5

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