PRMT5-IN-18

• Description:

  PRMT5-IN-18 (Compound 002) is a potent PRMT5 inhibitor that can be used for the research of a disease mediated by PRMT5, such as cancer[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-18.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C[C@@H](O)[C@H]2NCC3=C(C=CC=C3)C2)CCN(CC)C4=CC(C(N(CC5)CCC65CC(OC)C6)=O)=CC=C14

• Molecular Formula:

  C32H42N4O4

• Molecular Weight:

  546.70

• References & Citations:

  [1]Tetrahydroisoquinoline compounds and use thereof. WO2022002142A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PRMT5

• CAS Number:

  [2756849-68-8]