PRMT5-IN-32

• Description:

  PRMT5-IN-32 is an inhibitor of PRMT5. PRMT5-IN-32 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].

• UNSPSC:

  12352005

• Target:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/prmt5-in-32.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=CC(F)=CC=C2[C@@]3(C(N(CC3)CC4=C(C=C(C(F)=C4)F)F)=O)N1CC5=CC6=C(C)C=C(N)N=C6N5

• Molecular Formula:

  C27H21F4N5O2

• Molecular Weight:

  523.48

• References & Citations:

  [1]James Michael Smith, et al. Spirocyclic compounds. United States, US20230357279A1. 2023-11-09.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2918815-34-4]