PRMT5-IN-32

• Description :

  PRMT5-IN-32 is an inhibitor of PRMT5. PRMT5-IN-32 inhibits HCT116 cell proliferation with an IC 50 of 0.13 μM[1].

• CAS Number :

  [2918815-34-4]

• UNSPSC :

  12352005

• Target :

  Histone Methyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/prmt5-in-32.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1C2=CC(F)=CC=C2[C@@]3(C(N(CC3)CC4=C(C=C(C(F)=C4)F)F)=O)N1CC5=CC6=C(C)C=C(N)N=C6N5

• Molecular Formula :

  C27H21F4N5O2

• Molecular Weight :

  523.48

• References & Citations :

  [1]James Michael Smith, et al. Spirocyclic compounds. United States, US20230357279A1. 2023-11-09.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported