PL-017 (TFA)

• Description :

  PL-017 TFA is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 TFA produces long-lasting, reversible analgesia in rats[1].

• UNSPSC :

  12352209

• Target :

  Opioid Receptor

• Type :

  Peptides

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/pl-017-tfa.html

• Solubility :

  H2O

• Smiles :

  O=C(N1[C@H](CCC1)C(N)=O)[C@H](CC2=CC=CC=C2)N(C)C([C@H]3N(CCC3)C([C@@H](N)CC4=CC=C(O)C=C4)=O)=O.OC(C(F)(F)F)=O

• Molecular Formula :

  C31H38F3N5O7

• Molecular Weight :

  649.66

• References & Citations :

  [1]K J Chang, et al. Potent morphiceptin analogs: structure activity relationships and morphine-like activities. J Pharmacol Exp Ther. 1983 Nov;227 (2) :403-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• Isoform :

  μ Opioid Receptor/MOR