Products for Research Use Only
RegisterLogin

PL-017

CAT: 0804-HY-P1338Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-P1338Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
PL-017 is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 produces long-lasting, reversible analgesia in rats[1].
CAS Number
83397-56-2
UNSPSC
12352209
Target
Opioid Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pl-017.html
Solubility
H2O
Smiles
O=C(N1[C@H](CCC1)C(N)=O)[C@H](CC2=CC=CC=C2)N(C)C([C@H]3N(CCC3)C([C@@H](N)CC4=CC=C(O)C=C4)=O)=O
Molecular Formula
C29H37N5O5
Molecular Weight
535.63
References & Citations
[1]K J Chang, et al. Potent morphiceptin analogs: structure activity relationships and morphine-like activities. J Pharmacol Exp Ther. 1983 Nov;227 (2) :403-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR

Chemical Information

morphiceptin, N-Me-Phe(3)-

RN given refers to D-prolinamide, all L-isomer

CAS Number83397-56-2
PubChem CID115335
IUPAC Name(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[(2R)-2-carbamoylpyrrolidin-1-yl]-1-oxo-3-phenylpropan-2-yl]-N-methylpyrrolidine-2-carboxamide
Molecular FormulaC29H37N5O5
Molecular Weight535.6
XLogP1.5
Topological Polar Surface Area150
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Heavy Atom Count39
Formal Charge0
Complexity885
SMILES
CN([C@@H](CC1=CC=CC=C1)C(=O)N2CCC[C@@H]2C(=O)N)C(=O)[C@@H]3CCCN3C(=O)[C@H](CC4=CC=C(C=C4)O)N
InChI
InChI=1S/C29H37N5O5/c1-32(25(18-19-7-3-2-4-8-19)29(39)33-15-5-9-23(33)26(31)36)28(38)24-10-6-16-34(24)27(37)22(30)17-20-11-13-21(35)14-12-20/h2-4,7-8,11-14,22-25,35H,5-6,9-10,15-18,30H2,1H3,(H2,31,36)/t22-,23+,24-,25-/m0/s1
InChIKey
JAKBYSTWCHUQOK-NDBXHCKUSA-N
Chemical Structure
2D Structure
2D structure of morphiceptin, N-Me-Phe(3)-
CAS: 83397-56-2
CID: 115335
Formula: C29H37N5O5
MW: 535.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight535.6
XLogP31.5
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Exact Mass535.27946930
Monoisotopic Mass535.27946930
Topological Polar Surface Area150 Ų
Heavy Atom Count39
Formal Charge0
Complexity885
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-W419140-01AND-017
HY-121642SL-017
HY-174212MXC-017
HY-18051CXL 017
HY-147082-01GA-017
HY-19291DL-017
HY-118821JTC-017
HY-171715PL-13
HY-137798-01Chromozym PL
HY-107468-01PL-100

Alternative Products

CatalogName
M30590-01PL 017
TP1958PL-017
MBS5817824PL-017 TFA
GTR19281005-01AND-017
T210882-01MXC-017
T24216-01JTC-017
C01502-10mM/1mLGA-017
T34657SL-017

Popular Products