PL-017

• UNSPSC Description:

  PL-017 is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 produces long-lasting, reversible analgesia in rats[1].

• Target Antigen:

  Opioid Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/pl-017.html

• Solubility:

  H2O

• Smiles:

  O=C(N1[C@H](CCC1)C(N)=O)[C@H](CC2=CC=CC=C2)N(C)C([C@H]3N(CCC3)C([C@@H](N)CC4=CC=C(O)C=C4)=O)=O

• Molecular Weight:

  535.63

• References & Citations:

  [1]K J Chang, et al. Potent morphiceptin analogs: structure activity relationships and morphine-like activities. J Pharmacol Exp Ther. 1983 Nov;227(2):403-8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  83397-56-2