TMX-4102

CAT: 0804-HY-174296Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174296Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMX-4102 is a highly selective phosphatidylinositol 5-phosphate 4-kinase type II gamma (PIP4K2C) binder. TMX-4102 has binding activity to PIP4K2C (KD = 0.45 nM) and has no significant effect on other lipid and non-lipid kinases.TMX-4102 specifically binds to PIP4K2C, regulating its scaffold function rather than its enzymatic activity. TMX-4102 can be used as a tool molecule to study the biological function and potential therapeutic value of PIP4K2C[1].
UNSPSC
12352005
Target
PI5P4K
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Smiles
ClC1=CN=C(NC2=CC3=C(OC[C@]([H])(CC4)N3C4=O)N=C2)N=C1C5=CC=CC(C6=CC=CC=C6)=C5
Molecular Formula
C26H20ClN5O2
Molecular Weight
469.92
References & Citations
[1]Teng M, et al. Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader. Angew Chem Int Ed Engl. 2023 Apr 24;62 (18) :e202302364.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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