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TMX-2172

CAT: 0013-GTR19242027-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19242027-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMX-2172 is a selective CDK2/CDK5 degrader with minimal off-target effects, demonstrating potent anti-proliferative activity in CCNE1-high ovarian cancer models like OVCAR8 cells. This lead compound supports research into targeted protein degradation as a therapeutic strategy for cyclin E1-amplified cancers in both in vitro and in vivo settings.
CAS Number
2488892-09-5
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
O=C (N) C=1C (F) =CC=CC1NC2=NC (=NC=C2Br) NC3=CC=C (C=C3C) S (=O) (=O) NCCOCCOCCOCCOCCNC4=CC=CC=5C (=O) N (C (=O) C45) C6C (=O) NC (=O) CC6
Molecular Formula
C41H45BrFN9O11S
Molecular Weight
970.82
Storage Conditions
-20°C
Notes
For research use only.

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