TMX-3013

CAT: 0804-HY-151071-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-151071-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TMX-3013 is a CDKs inhibitor capable of inhibiting the activity of CDK1, CDK2, CDK4, CDK5, and CDK6, with IC50 values of 0.9 nM, [1].
CAS Number
[2488761-18-6]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tmx-3013.html
Purity
98.0200
Smiles
NC(C1=C(C=CC=C1NC2=NC(NC3=CC=C(C=C3)S(N)(=O)=O)=NC=C2Br)F)=O
Molecular Formula
C17H14BrFN6O3S
Molecular Weight
481.30
References & Citations
[1]Teng M, et al. Development of CDK2 and CDK5 dual degrader TMX‐2172[J]. Angewandte Chemie, 2020, 132 (33) : 13969-13974.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK2; CDK4; CDK5; CDK6

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