PDIC-NC

• Description :

  PDIC-NC is a STING agonist. PDIC-NC is cytotoxic to tumor cells and induces ROS explosion, apoptosis and autophagy. PDIC-NC has lung specific distribution and can be used in the study of lung cancer[1][2].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Autophagy; Reactive Oxygen Species (ROS) ; STING

• Related Pathways :

  Apoptosis; Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research :

  Cancer

• Smiles :

  O=C1C2=CC(Cl)=C3C4=C(C=C5C(N(CCN(C)C)C(C6=CC(Cl)=C(C4=C56)C7=C3C2=C(C(N1CCN(C)C)=O)C=C7Cl)=O)=O)Cl.Cl.Cl

• Molecular Formula :

  C32H26Cl6N4O4

• Molecular Weight :

  743.29

• References & Citations :

  [1]Liu Z, et al. Regulating Twisted Skeleton to Construct Organ-Specific Perylene for Intensive Cancer Chemotherapy. Angew Chem Int Ed Engl. 2021 Jul 12;60 (29) :16215-16223.|[2]Zhao X, et al. Sulfonated Perylene as Three-in-One STING Agonist for Cancer Chemo-Immunotherapy. Angew Chem Int Ed Engl. 2024 Mar 11;63 (11) :e202318799.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2633013-75-7]