SIAIS630121-NC

• UNSPSC Description:

  SIAIS630121-NC is a negative control for NAMPT (nicotinamide phosphoribosyltransferase) degrader SIAIS630121(Sturcture Note:(Blue: Cereblon ligand Thalidomide (HY-14658) analogue (HY-138793), Black: linker；Pink: Nampt inhibitor FK866 (HY-50876))[1].

• Target Antigen:

  PROTACs

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/siais630121-nc.html

• Smiles:

  O=C(NCCCCC1CCN(C(C2=CC=C(N3CCN(CCCCCCC#CC4=CC=CC5=C4CN(C(CC6)C(N(C)C6=O)=O)C5=O)CC3)C=C2)=O)CC1)/C=C/C7=CC=CN=C7

• Molecular Weight:

  840.06

• References & Citations:

  [1]Xiaotong Zhu, et al. Addressing the Enzyme-independent tumor-promoting function of NAMPT via PROTAC-mediated degradation.Cell Chem Biol

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported