NC-2100

• Description:

  NC-2100 is a PPAR activator. NC-2100 can effectively reduce the plasma glucose and triglyceride levels of obese KKAy mice. NC-2100 can induce UCP1 and UCP2 expression in mesenteric and subcutaneous WAT of mice. NC-2100 can be used in research related to type 2 diabetes[1].

• UNSPSC:

  12352005

• Target:

  PPAR

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease

• Smiles:

  O=C(N1)SC(CC2=CC3=CC=C(OCC4=CC=CC=C4)C=C3N=C2)C1=O

• Molecular Formula:

  C20H16N2O3S

• Molecular Weight:

  364.42

• References & Citations:

  [1]Fukui Y, et al. A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice. Diabetes. 2000 May;49 (5) :759-67.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [179068-64-5]