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PDIC-NN dimethanesulfonate

CAT: 0013-GTR19263948-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19263948-01Size:50 mg
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Description
PDIC-NN dimethanesulfonate (PDIC-NS) is a STING activator with anticancer properties. It increases the levels and stability of endogenous cyclic dinucleotides (CDN) . PDIC-NN dimethanesulfonate triggers a burst of reactive oxygen species (ROS) and causes significant mitochondrial damage. It induces apoptosis and inhibits DNA replication. Additionally, it activates the cGAS-STING signaling pathway, enhancing the immunogenicity of tumor cells and triggering a strong innate immune response.
CAS Number
3040919-39-6
Field of Research
Cell Biology, Immunology & Inflammation
Smiles
O=C1C2=CC (Cl) =C3C4=C (Cl) C=C5C (=O) N (C (=O) C6=CC (Cl) =C (C=7C (Cl) =CC (C (=O) N1CCN (C) C) =C2C37) C4=C56) CCN (C) C.O=S (=O) (O) C
Molecular Formula
C33H28Cl4N4O7S
Molecular Weight
766.48
Storage Conditions
-20°C
Notes
For research use only.

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