NC-182

• UNSPSC Description:

  NC-182 是一种抗肿瘤剂和 DNA 插入剂，对 B 型 DNA 有偏好性。NC-182 还能够促进 Z 型 DNA 解旋为 B 型。NC-182 针对多药介入和敏感肿瘤有强效抑制作用。

• Target Antigen:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/nc-182.html

• Smiles:

  O=C(OC)C1=CC2=NC3=C(C(O)=C4C(C=CC=C4)=C3N=C2C=C1OC)C(NCCN(C)C)=O

• Molecular Weight:

  448.47

• References & Citations:

  [1]DNA-binding characterization of a novel anti-tumour benzo[a]phenazine derivative NC-182: spectroscopic and viscometric studies

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  106224-67-3