NC-182

• Description:

  NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors.

• UNSPSC:

  12352005

• Target:

  DNA Alkylator/Crosslinker

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nc-182.html

• Smiles:

  O=C (OC) C1=CC2=NC3=C (C (O) =C4C (C=CC=C4) =C3N=C2C=C1OC) C (NCCN (C) C) =O

• Molecular Formula:

  C24H24N4O5

• Molecular Weight:

  448.47

• References & Citations:

  [1]DNA-binding characterization of a novel anti-tumour benzo[a]phenazine derivative NC-182: spectroscopic and viscometric studies

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  106224-67-3