NC-182

CAT: 0804-HY-118138Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-118138Size:1 Each
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Description
NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors.
CAS Number
[106224-67-3]
UNSPSC
12352005
Target
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nc-182.html
Smiles
O=C(OC)C1=CC2=NC3=C(C(O)=C4C(C=CC=C4)=C3N=C2C=C1OC)C(NCCN(C)C)=O
Molecular Formula
C24H24N4O5
Molecular Weight
448.47
References & Citations
[1]DNA-binding characterization of a novel anti-tumour benzo[a]phenazine derivative NC-182: spectroscopic and viscometric studies
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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