NC-182

• Description :

  NC-182 is an anti-tumor agent and DNA intercalator with a preference for B-form DNA. NC-182 can also promote the unwinding of Z-form DNA to B-form. NC-182 has a potent inhibitory effect on multidrug-resistant and sensitive tumors.

• UNSPSC :

  12352005

• Target :

  DNA Alkylator/Crosslinker

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/nc-182.html

• Smiles :

  O=C(OC)C1=CC2=NC3=C(C(O)=C4C(C=CC=C4)=C3N=C2C=C1OC)C(NCCN(C)C)=O

• Molecular Formula :

  C24H24N4O5

• Molecular Weight :

  448.47

• References & Citations :

  [1]DNA-binding characterization of a novel anti-tumour benzo[a]phenazine derivative NC-182: spectroscopic and viscometric studies

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [106224-67-3]