NC-001

• Description :

  NC-001 is a selective apoptosis inducer targeting renal proximal tubular cells and renal cancer cells. NC-001 inhibits tumor growth in clear cell renal cell carcinoma (CCRCC) xenograft models. NC-001 is promising for research of metastatic renal cell carcinoma[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Field of Research :

  Cancer

• Smiles :

  O=C([C@H]1N(C([C@H](C)NC(CN=[N+]=[N-])=O)=O)CCC1)N[C@@H](CCCC)C(N[C@@H](CC(C)C)C([C@]2(C)OC2)=O)=O

• Molecular Formula :

  C25H41N7O6

• Molecular Weight :

  535.64

• References & Citations :

  [1]Hedman H, et al. Abstract LB-118: NC-001 induces apoptosis and necrosis in clear cell renal cell carcinoma in vitro and in a xenograft model in vivo[J]. Cancer Research, 2012, 72 (8_Supplement) : LB-118-LB-118.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1237540-68-9]