APL-1081

• Target :

  Drug-Linker Conjugates for ADC

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  APL-1081 (Mal-Exo-EVC-MMAE) forms part of an antibody-drug conjugate (ADC) . It consists of the ADC linker (peptide Mal-Exo-EEVC) coupled with the potent microtubule polymerization inhibitor MMAE.

• Smiles :

  [C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OC(C(NCCCCCN3C(=O)C=CC3=O)=O)C4=CC=C(NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(C)=O)=O)[C@@H](C)C)=O)CCCNC(N)=O)=O)C=C4)=O)C)C(C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

• Molecular Formula :

  C75H115N13O19

• Molecular Weight :

  1502.79

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2921735-80-8