APL-1092

CAT: 0804-HY-169324Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-169324Size:1 Each
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Description
APL-1092 (Mal-Exo-EEVC-Exatecan) is a drug-linker conjugate for ADC, which contains Exatecan (HY-13631) (ADC payload) and a linker[1].
CAS Number
[2921735-91-1]
Product Name Alternative
Mal-Exo-EEVC-Exatecan
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apl-1092.html
Smiles
O=C(C=CC1=O)N1CCCCCNC(C(C2=CC=C(C=C2)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)=O)OC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O
Molecular Formula
C65H77FN12O19
Molecular Weight
1349.37
References & Citations
[1]Watanabe T, et al. Exo-Cleavable Linkers: Enhanced Stability and Therapeutic Efficacy in Antibody-Drug Conjugates. J Med Chem. 2024 Oct 24;67 (20) :18124-18138.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported

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