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APL-1091

CAT: 0931-T203603-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T203603-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2921735-87-5
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
APL-1091 (Mal-Exo-EEVC-MMAE) is an ADC toxic molecule-linker conjugate, designed for drug-linker conjugates in ADC applications. It is composed of a Mal-Exo-EEVC linker coupled with MMAE (a microtubule inhibitor) . APL-1091 is suitable for use in ADC synthesis.
Smiles
[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OC(C(NCCCCCN3C(=O)C=CC3=O)=O)C4=CC=C(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCC(O)=O)NC(C)=O)=O)CCC(O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C4)=O)C)[C@@H](C)C)=O)[C@@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Molecular Formula
C80H122N14O22
Molecular Weight
1631.91
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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