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PBS-1086

CAT: 0931-T71147-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T71147-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1246668-32-5
Target
Others
Related Pathways
Others
Bioactivity
PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.
Smiles
OC1C2C(O2)C(=O)C=C1NC(=O)C3=CC=4C(NC3=O)=CC=CC4
Molecular Formula
C16H12N2O5
Molecular Weight
312.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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