PBS-1086

• Target :

  Others

• Related Pathways :

  Others

• Bioactivity :

  PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-?B pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.

• Smiles :

  OC1C2C(O2)C(=O)C=C1NC(=O)C3=CC=4C(NC3=O)=CC=CC4

• Molecular Formula :

  C16H12N2O5

• Molecular Weight :

  312.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1246668-32-5