CC-1088

• Target:

  Others

• Related Pathways:

  Others

• Bioactivity:

  CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs) . SelCIDs inhibit phosphodiesterase-4 (PDE 4), an enzyme involved in tumor necrosis factor alpha (TNF alpha) production. CC-1088 inhibits production of the cytokines vascular endothelial growth factor (VEGF) (a pro-angiogenic factor) and interleukin-6 (IL-6) .

• Smiles:

  NC(=O)CC(N1C(=O)c2ccccc2C1=O)c1ccccc1

• Molecular Formula:

  C17H14N2O3

• Molecular Weight:

  294.31

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  467421-06-3