RIPK1-IN-16

CAT: 0931-T81269-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T81269-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2561431-77-2

Target

RIP kinase

Related Pathways

NF-κB, Apoptosis

Bioactivity

RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo, protecting mice from TNF-induced systemic inflammatory response syndrome and sepsis [1].

Smiles

CN1C=2C(OC[C@H](NC(=O)C=3NC(CC4=CC=CC=C4)=NN3)C1=S)=CC=CC2

Molecular Formula

C20H19N5O2S

Molecular Weight

393.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-156367	RIPK1-IN-16
574852-01	RIPK1
M33106-01	RIPK1-IN-4
HY-179235	RIPK1-IN-37
ASD98244-01	RIPK1-IN-7
HY-162097	RIPK1-IN-20
HY-126296	RIPK1-IN-3
HY-169107	RIPK1-IN-25
HY-179680	RIPK1-IN-38
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RIPK1-IN-16

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