Products for Research Use Only
RegisterLogin

RIPK1-IN-38

CAT: 0804-HY-179680Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-179680Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RIPK1-IN-38 is an orally active RIPK1 inhibitor with an IC50 value of 27 nM. RIPK1-IN-38 can inhibit the phosphorylation of RIPK1 and its downstream signaling molecules RIPK3 and MLKL. RIPK1-IN-38 exhibits anti-necroptotic activity. RIPK1-IN-38 has excellent anti-inflammatory efficacy in both the SIRS model and GVHD model. RIPK1-IN-38 can be used for the research of inflammatory and immune-related diseases[1].
CAS Number
3092834-30-2
UNSPSC
12352005
Target
Interleukin Related; Lactate Dehydrogenase; Mixed Lineage Kinase; Necroptosis; RIP kinase
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@@H](C)C1=CC=C(F)C=C1)C2=C3N(C=CC(C4=CC5=C(N=C(NC(C6CC6)=O)S5)C=C4)=C3)N=C2
Molecular Formula
C27H22FN5O2S
Molecular Weight
499.56
References & Citations
[1]Zhang C, et al. Discovery of benzothiazole derivatives as novel orally receptor-interacting protein kinase 1 (RIPK1) inhibitors for inflammatory disease therapy. Eur J Med Chem. 2026;302 (Pt 3) :118380.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-6; RIPK1

Related Products

CatalogName
HY-175007RIPK1-IN-32
HY-179235RIPK1-IN-37
HY-169107RIPK1-IN-25
HY-162097RIPK1-IN-20
HY-126296RIPK1-IN-3
HY-156367RIPK1-IN-16
HY-144277RIPK1-IN-12
HY-146758RIPK1-IN-14
HY-178762SRIPK1-IN-35
HY-144276RIPK1-IN-11

Alternative Products

CatalogName
GTR19275479-01RIPK1-IN-38
574852-01RIPK1
BA3507-10RIPK1-IN-4
ASD98244-01RIPK1-IN-7
70R-21675RIPK1 antibody
T211437-01RIPK1-IN-32
T208885-01RIPK1-IN-20
T204483-01RIPK1-IN-28
T200682-01RIPK1-IN-24
T62762-01RIPK1-IN-11

Popular Products