RIPK1-IN-23

• Target :

  Necroptosis|||RIP kinase

• Related Pathways :

  Apoptosis|||NF-?B

• Bioactivity :

  RIPK1-IN-23 (compound 19) is an RIPK1 inhibitor with potent anti-necroptotic effects in HT-29 cells (EC50 = 1.7 nM) . Additionally, RIPK1-IN-23 exhibits anti-inflammatory properties.

• Smiles :

  CN1C=2C(=CC=C(C2)C3=CC=C(C#N)C=C3)OC[C@H](NC(=O)C=4NC(CC5=CC=CC=C5)=NN4)C1=O

• Molecular Formula :

  C27H22N6O3

• Molecular Weight :

  478.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3031534-16-1