RIPK1-IN-11

CAT: 0931-MF-0139193-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0139193-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2173557-02-1
Target
Others|||RIP kinase
Related Pathways
NF-?B|||Apoptosis|||Others
Bioactivity
RIPK1-IN-11 is an orally active RIPK1 inhibitor with a Kd value of 9.2 nM and an IC50 value of 67 nM. RIPK1-IN-11 inhibits necrosis in human and mouse cells and exhibits anti-inflammatory effects.
Smiles
N(C(=O)C1CC1)C=2SC=3C(N2)=CC=C(C3)C=4C=C(NC(OC5CCOCC5)=O)C(C)=NC4
Molecular Formula
C23H24N4O4S
Molecular Weight
452.53
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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