RIPK1-IN-32

CAT: 0931-T211437-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T211437-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Interleukin, NF-κB, p38 MAPK, TNF, RIP kinase

Related Pathways

NF-κB, MAPK, Apoptosis, Immunology/Inflammation

Bioactivity

RIPK1-IN-32 is an RIPK inhibitor with anti-inflammatory properties. It inhibits nitric oxide (NO) release, with an IC50 of 3.26 μM. Additionally, RIPK1-IN-32 disrupts the RIPK1/NF-κB/MAPK signaling pathway, preventing nuclear translocation of p65 and c-fos, leading to reduced expression of TNF-α and IL-6 and significantly alleviating acute liver injury related to sepsis. This compound is useful for studies on acute liver injury and sepsis.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-175007	RIPK1-IN-32
574852-01	RIPK1
BA3507-10	RIPK1-IN-4
HY-179235	RIPK1-IN-37
ASD98244-01	RIPK1-IN-7
70R-21675	RIPK1 antibody
HY-169107	RIPK1-IN-25
HY-162097	RIPK1-IN-20
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RIPK1-IN-32

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