P-gp/BCRP-IN-2

CAT: 0931-T79353-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T79353-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

P-gp, BCRP, Others

Related Pathways

Neuroscience, Membrane transporter/Ion channel, Others

Bioactivity

P-gp/BCRP-IN-2 (compound 15), an oxadiazole derivative, functions as a dual inhibitor targeting both the ABC transporter P-glycoprotein (IC50: 1.6 nM) and BCRP (IC50: 600 nM) . Additionally, it bolsters the anti-proliferative impact of Doxorubicin in the drug-resistant HT29/DX and MDCK-MDR1 human adenocarcinoma colon cancer cell lines [1].

Molecular Formula

C32H35N3O6

Molecular Weight

557.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-155152	P-gp/BCRP-IN-2
MBS5805938	P-gp/BCRP-IN-1
HY-146117	P-gp modulator 2
MBS5815035	P-gp Inhibitor 2
HY-169860-01	BCRP-IN-2
HY-174324	VEGFR-2/P-gp-IN-1
HY-175522	P-gp-IN-31
GTR19272890-01	P-gp-IN-32
HY-175206	P-gp-IN-30
GTR19273727-01	P-gp-IN-33

P-gp/BCRP-IN-2

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