P-gp-IN-32

CAT: 0013-GTR19272890-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19272890-01Size:50 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

P-gp-IN-32 is a P-glycoprotein (P-gp) inhibitor with low cytotoxicity, demonstrating significant multidrug resistance (MDR) reversal activity against doxorubicin in MCF7/ADR cells. It has an IC50 value of 0.11 μM and a resistance reversal factor (RF) of 215.9. P-gp-IN-32 interacts directly with P-gp, inducing conformational changes and inhibiting its efflux function. This compound is applicable in cancer research, including studies on breast cancer.

CAS Number

2918249-59-7

Smiles

O=C (C1=CC2=CC (=CC=C2N1CC3=CC=C (OC) C=C3) C=4C=CC=C (OC) C4) N5CC6=CC (OC) =C (OC) C=C6CC5

Molecular Formula

C35H34N2O5

Molecular Weight

562.67

Storage Conditions

-20°C

Notes

For research use only.

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P-gp-IN-32

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