P-gp-IN-31

CAT: 0931-T212471-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T212471-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

P-gp, Apoptosis

Related Pathways

Neuroscience, Membrane transporter/Ion channel, Apoptosis

Bioactivity

P-gp-IN-31 is an inhibitor of P-glycoprotein (P-gp) with IC50 values of 0.42 μM for KB cells and 0.43 μM for MDR KBvin cells. This compound effectively overcomes P-gp mediated drug efflux, exhibiting collateral sensitivity through P-gp downregulation. P-gp-IN-31 inhibits cell proliferation, induces apoptosis (apoptosis), and arrests the cell cycle in the G2/M phase. It is applicable in cancer research, particularly for multidrug-resistant (MDR) malignancies.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-175522	P-gp-IN-31
GTR19272890-01	P-gp-IN-32
HY-175206	P-gp-IN-30
GTR19273727-01	P-gp-IN-33
HY-178349	P-gp inhibitor 30
HY-157484	P-gp inhibitor 19
HY-146117	P-gp modulator 2
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HY-157330	P-gp inhibitor 16
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P-gp-IN-31

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