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BCRP-IN-2

CAT: 0931-T203499-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203499-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2953730-35-1
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Bioactivity
BCRP-IN-2 is a compound with BCRP inhibitory activity, exhibiting enhanced inhibition of BCRP upon UV activation. It serves as a valuable probe for studying interactions between quinazoline amine derivatives and BCRP, and it stimulates ATP hydrolysis of the BCRP transporter, leading to increased mitoxantrone accumulation in BCRP-overexpressing H460/MX20 cells.
Smiles
[N-]=[N+]=NC1=CC=C(C=C1)NC2=NC(=NC3=CC=CC=C32)C=4C=CN=CC4
Molecular Formula
C19H13N7
Molecular Weight
339.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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