P-gp/CDK2-IN-1

CAT: 0931-T210177-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T210177-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

P-gp, CDK

Related Pathways

Neuroscience, Cell Cycle/Checkpoint, Membrane transporter/Ion channel

Bioactivity

P-gp/CDK2-IN-1 (Compound 4j) is an inhibitor of P-glycoprotein (P-gp) and cyclin-dependent kinase 2 (CDK2) . It inhibits the proliferation of cancer cell lines SW-480 and MCF-7, with IC50 values of 38.6 μM and 26.6 μM, respectively. In the DPPH assay, P-gp/CDK2-IN-1 demonstrates antioxidant activity with an EC50 of 580 μM.

Molecular Formula

C21H23NO8

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-161776	P-gp/CDK2-IN-1
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P-gp/CDK2-IN-1

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