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Keap1-Nrf2-IN-15

CAT: 0931-T78697-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T78697-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2456295-45-5
Target
Nrf2, Others
Related Pathways
Others, Immunology/Inflammation
Bioactivity
Keap1-Nrf2-IN-15 (Compound 24a) is a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, with IC50 values of 77 nM in a fluorescence polarization (FP) assay and 2.5 nM in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay [1].
Smiles
N(S(=O)(=O)C1=CC=C(OC)C=C1)(CC(O)=O)C=2C3=C(C(N(S(=O)(=O)C4=CC=C(OC)C=C4)CC(O)=O)=CC2CCCN5C(=O)C=6C(C5=O)=CC=CC6)C=CC=C3
Molecular Formula
C39H35N3O12S2
Molecular Weight
801.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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