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Keap1-Nrf2-IN-18

CAT: 0931-T209309-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209309-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Nrf2
Related Pathways
Immunology/Inflammation
Bioactivity
Keap1-Nrf2-IN-18 (Compound 22) is an orally active inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI), demonstrating favorable pharmacokinetic (PK) properties and enhanced in vivo efficacy in rats. In structure-activity relationship (SAR) studies, Keap1-Nrf2-IN-18 exhibits the strongest inhibitory activity (KD = 0.0029 μM) .
Molecular Formula
C27H29FN2O4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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