Keap1-Nrf2-IN-28

• Target:

  Nrf2

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  Keap1-Nrf2-IN-28 (SG16) is an orally active inhibitor of Keap1-Nrf2. It demonstrates antioxidant properties and upregulates the expression of Nrf2, HO-1, GCLM, and Akr1c1. Additionally, Keap1-Nrf2-IN-28 can mitigate acute liver injury induced by APAP.

• Smiles:

  O=C1C=C(OC2=CC(=CC=C12)NS(=O)(=O)C3=CC=C(F)C=C3)C=4C=CC(OC)=CC4

• Molecular Formula:

  C22H16FNO5S

• Molecular Weight:

  425.43

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3075750-60-3