KTX-955

• Target :

  PROTACs|||IRAK|||Others

• Related Pathways :

  Immunology/Inflammation|||Others|||PROTAC|||NF-?B

• Bioactivity :

  KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].

• Smiles :

  CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CC[C@H](CN2CCC(CC2)O[C@H]2C[C@@H](C2)Nc2cccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c23)CC1

• Molecular Formula :

  C46H51F3N8O7

• Molecular Weight :

  884.94

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2573302-50-6