KTX-497

CAT: 0931-T74666-01Size: 5 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T74666-01Size:5 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2432993-46-7

Target

PROTACs, IRAK, Others

Related Pathways

Immunology/Inflammation, NF-κB, Others, PROTAC

Bioactivity

KTX-497, an IRAK4 degrader, demonstrates a potent DC50 value of 3 nM. It is utilized in oncology research[1].

Smiles

CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CC[C@H](CN2CCC3(CC(C3)Nc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)CC1

Molecular Formula

C45H49F3N8O6

Molecular Weight

854.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products