KTX-497

• Target :

  PROTACs|||IRAK|||Others

• Related Pathways :

  Immunology/Inflammation|||NF-?B|||Others|||PROTAC

• Bioactivity :

  KTX-497, an IRAK4 degrader, demonstrates a potent DC50 value of 3 nM. It is utilized in oncology research[1].

• Smiles :

  CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CC[C@H](CN2CCC3(CC(C3)Nc3cccc4C(=O)N(C5CCC(=O)NC5=O)C(=O)c34)CC2)CC1

• Molecular Formula :

  C45H49F3N8O6

• Molecular Weight :

  854.92

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2432993-46-7