KTX-612

• Target:

  Others|||PROTACs|||IRAK

• Related Pathways:

  PROTAC|||Others|||NF-?B|||Immunology/Inflammation

• Bioactivity:

  KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].

• Smiles:

  CC(C)(O)c1cc2nn(cc2cc1NC(=O)c1cccc(n1)C(F)(F)F)[C@H]1CC[C@H](CN2CCC3(CC(CNc4cccc5C(=O)N(C6CCC(=O)NC6=O)C(=O)c45)C3)CC2)CC1

• Molecular Formula:

  C46H51F3N8O6

• Molecular Weight:

  868.94

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2573298-14-1