GNE-955

• Target :

  Pim

• Related Pathways :

  Chromatin/Epigenetic|||JAK/STAT signaling

• Bioactivity :

  GNE-955 is a potent and orally active inhibitor of pan Pim kinase, with inhibition constants (Kis) of 0.018 nM, 0.11 nM, and 0.08 nM for Pim1, Pim2, and Pim3, respectively.

• Smiles :

  O(C)C=1C(=NC(N2C=3C(C=N2)=CN=C(C3)C4=NC(C)=CN=C4)=CC1)N5C[C@@H](N)CCC5

• Molecular Formula :

  C22H24N8O

• Molecular Weight :

  416.48

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1527523-39-2