TMX-2164

• Target:

  Bcl-2 Family|||Others

• Related Pathways:

  Others|||Apoptosis

• Bioactivity:

  TMX-2164, a potent and irreversible inhibitor of B-cell lymphoma 6 (BCL6), demonstrates an IC50 of 152 nM, indicating strong inhibitory efficacy. It exhibits prolonged target engagement and effectively inhibits cell proliferation.

• Smiles:

  O(C)C1=C2C(=CC(NC3=NC(NCC4=CC(S(F)(=O)=O)=CC=C4)=NC=C3Cl)=C1)C=C(OCC(NC)=O)C(=O)N2C

• Molecular Formula:

  C25H24ClFN6O6S

• Molecular Weight:

  591.01

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2418022-85-0