TMX-2039

• Target:

  Ligands for Target Protein for PROTAC|||CDK

• Related Pathways:

  PROTAC|||Cell Cycle/Checkpoint

• Bioactivity:

  TMX-2039 is a pan-CDK inhibitor that targets cell cycle CDKs (CDK1, CDK2, CDK4, CDK5, and CDK6) and transcription CDKs (CDK7 and CDK9), with IC50 values of 2.6, 1.0, 52.1, 0.5, 35.0, 32.5, and 25 nM, respectively. It serves as a ligand for the target protein in PROTAC applications.

• Smiles:

  O=C(N)C=1C(F)=CC=CC1NC2=NC(=NC=C2Br)NC3CCN(CC3)S(=O)(=O)C

• Molecular Formula:

  C17H20BrFN6O3S

• Molecular Weight:

  487.347

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2488892-01-7