TMX-4116

• Target :

  Molecular Glues|||Casein Kinase

• Related Pathways :

  Stem Cells|||PROTAC|||Metabolism

• Bioactivity :

  TMX-4116 is a casein kinase 1? (CK1?) degrader that preferentially targets CK1? for degradation in cell lines including MOLT4, Jurkat, and MM.1S. TMX-4116 exhibits potent activity with degradation concentration 50 values (DC50s) below 200 nM. TMX-4116 is employed in the study of multiple myeloma and protein degradation strategies.

• Smiles :

  O(C)C=1C(=CSC1C(=O)N2CCCC2)C3=CN(N=N3)C4C(=O)NC(=O)CC4

• Molecular Formula :

  C17H19N5O4S

• Molecular Weight :

  389.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2766385-56-0