NF-κB-IN-11

CAT: 0931-T79671-01Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0931-T79671-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

2768833-35-6

Target

NF-κB

Related Pathways

NF-κB

Bioactivity

NF-κB-IN-11 (Compound 3i) is an inhibitor of NF-κB, effectively blocking TNF-α-induced NF-κB pathway activation and nuclear translocation of NF-κB, alongside reducing expression levels of phospho-IKK, IκBα, and NF-κB p65. Demonstrating anti-inflammatory properties, it mitigates dextran sulfate sodium-induced colitis in mice and exhibits a maximum tolerated dose (MTD) exceeding 1852 mg/kg in acute toxicity assays when administered orally (p.o.) [1].

Smiles

C(OC)(=O)C=1C2C(C#CC3=CC=C(C)C=C3)CC(O2)C1C(OC)=O

Molecular Formula

C19H18O5

Molecular Weight

326.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Related Products

Catalog	Name
T208821-01	NF-κB-IN-14
T89612-01	NF-κB-IN-17
T62060-01	NF-κB-IN-5
T78750-01	NF-κB-IN-10
T209749-01	NF-κB-IN-16
T205560-01	NF-κB-IN-19
T74799-01	NF-κB-IN-8
T209424-01	NF-κB-IN-15
T204218-01	NF-κB-IN-18
T60868	NF-κB-IN-4

Alternative Products

Catalog	Name
HY-155998-01	NF-κB-IN-11
MBS5821332	NF-kappaB-IN-11
60614	NF-κB Reporter Kit (NF-κB Signaling Pathway)
BA8604-1	NF-κB-IN-1
HY-144765-01	NF-κB-IN-4
HY-175833	NF-κB-IN-20
HY-158156	NF-κB-IN-16
HY-144744	NF-κB-IN-3
HY-149838	NF-κB-IN-9
HY-149248	NF-κB-IN-8

NF-κB-IN-11

Related Products

Alternative Products

Popular Products