NF-?B-IN-18

• Target:

  NF-?B

• Related Pathways:

  NF-?B

• Bioactivity:

  NF-?B-IN-18 (Compound 5k) is an orally active NF-?B inhibitor that suppresses the phosphorylation of p65 and demonstrates significant anti-inflammatory activity in mice with xylene-induced ear edema.

• Smiles:

  CC1(C=CC2=C3C(=C(C(=C2O1)C(=O)OC)OCC(=O)NC4=CC5=C(C=C4)N=CC=C5)C=CC(O3)(C)C)C

• Molecular Formula:

  C29H28N2O6

• Molecular Weight:

  500.542

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C