Exatecan Intermediate 7

CAT: 0931-MF-0122415-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0122415-01Size:10 mg
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CAS Number
182182-32-7
Target
ADC Cytotoxin
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
Exatecan Intermediate 7 is an intermediary in the production of Exatecan (DX-8951), a DNA topoisomerase I inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the synthesis of Antibody-Drug Conjugates (ADCs) .
Smiles
O=C1C=2C(=CC(F)=C(C2CCC1=NO)C)NC(=O)C
Molecular Formula
C13H13FN2O3
Molecular Weight
264.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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