Exatecan Intermediate 7

• Target:

  ADC Cytotoxin

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Exatecan Intermediate 7 is an intermediary in the production of Exatecan (DX-8951), a DNA topoisomerase I inhibitor with an IC50 value of 2.2 ?M (0.975 ?g/mL), utilized in cancer research. This intermediate is also employed in the synthesis of Antibody-Drug Conjugates (ADCs) .

• Smiles:

  O=C1C=2C (=CC (F) =C (C2CCC1=NO) C) NC (=O) C

• Molecular Formula:

  C13H13FN2O3

• Molecular Weight:

  264.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  182182-32-7