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Exatecan intermediate 11

CAT: 0931-T208436-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T208436-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ADC Cytotoxin, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Antibody-drug Conjugate/ADC Related
Bioactivity
Exatecanintermediate 11 is an intermediate compound used in the synthesis of Exatecan. Exatecan (DX-8951) is a frequently utilized cytotoxic component in the preparation of antibody-drug conjugates (ADC Cytotoxin) and serves as an inhibitor of DNA topoisomerase I (topoisomeraseI) with an IC50 of 2.2 μM.
Molecular Formula
C13H13FN2O3
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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