MOR modulator-1

• Target:

  Opioid Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity:

  MOR modulator-1 (compound 6) is a potent and selective modulator of the ? opioid receptor (MOR) . Compared to NAT (6?-configuration), MOR modulator-1 demonstrates improved opioid receptor selectivity, enhanced antagonistic effects in vivo, and overall reduced withdrawal symptoms. It connects to the ?, ?, and ? receptors with carboxamide linkers, showing Ki values of 0.25, 41.1, and 1.30 nM respectively.

• Smiles:

  O[C@]12[C@@]34C=5C (O[C@]3 ([C@@H] (NC (=O) C6=NC=CS6) CC1) [H]) =C (O) C=CC5C[C@]2 (N (CC7CC7) CC4) [H]

• Molecular Formula:

  C24H27N3O4S

• Molecular Weight:

  453.554

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2976336-81-7