MOR modulator-1

• Target :

  Opioid Receptor

• Related Pathways :

  Neuroscience|||GPCR/G Protein|||Endocrinology/Hormones

• Bioactivity :

  MOR modulator-1 (compound 6) is a potent and selective modulator of the ? opioid receptor (MOR) . Compared to NAT (6?-configuration), MOR modulator-1 demonstrates improved opioid receptor selectivity, enhanced antagonistic effects in vivo, and overall reduced withdrawal symptoms. It connects to the ?, ?, and ? receptors with carboxamide linkers, showing Ki values of 0.25, 41.1, and 1.30 nM respectively.

• Smiles :

  O[C@]12[C@@]34C=5C(O[C@]3([C@@H](NC(=O)C6=NC=CS6)CC1)[H])=C(O)C=CC5C[C@]2(N(CC7CC7)CC4)[H]

• Molecular Formula :

  C24H27N3O4S

• Molecular Weight :

  453.554

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2976336-81-7