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MOR-106

CAT: 0931-T9901A-1827-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T9901A-1827-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2304625-87-2
Target
Interleukin, NF-κB
Related Pathways
Immunology/Inflammation, NF-κB
Bioactivity
MOR-106 (MOR12743) is a humanized anti-IL-17C IgG1 monoclonal antibody. It works by specifically binding to IL-17C, thereby inhibiting the NF-κB signaling pathway, with an IC50 of 59 pM for human IL-17C and 55 pM for mouse IL-17C. MOR-106 effectively reduces skin inflammation and related inflammatory factors in animal models of psoriasis and atopic dermatitis.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C