EGFR-IN-161

CAT: 0013-GTR19258320-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19258320-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of the L858R/T790M/C797S mutant EGFR kinase, with an IC50 value of 0.87 nM. EGFR-IN-161 effectively inhibits tumor cell apoptosis, G1 phase arrest, and migration.

CAS Number

3031099-34-7

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

C (CCO) N1C=C (C=2C1=CC=CC2) C3=NC (NC4=C (OC) C=C (N (CCN (C) C) C) C (/N=C/C=5C (Cl) =C (Cl) N=CC5) =C4) =NC=C3

Molecular Formula

C33H36Cl2N8O2

Molecular Weight

647.597

Storage Conditions

-20°C

Notes

For research use only.

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T206760-01	EGFR-IN-161
BA1597-100	WT-161
RFA77420-01	N 161
HY-172964	KIM-161
T209721-01	RTx-161
T204979-01	V-161
T203623-01	AB-161
441888-01	ATN 161
MBS3845737-01	ATN-161
MBS3602418-01	CD 161

EGFR-IN-161

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