EGFR-IN-161

CAT: 0931-T206760-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T206760-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

3031099-34-7

Target

Apoptosis, EGFR

Related Pathways

Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Apoptosis

Bioactivity

EGFR-IN-161 (Compound DD-8) is a potent and reversible inhibitor of the L858R/T790M/C797S mutant EGFR kinase, with an IC50 value of 0.87 nM. EGFR-IN-161 effectively inhibits tumor cell apoptosis, G1 phase arrest, and migration.

Smiles

C(CCO)N1C=C(C=2C1=CC=CC2)C3=NC(NC4=C(OC)C=C(N(CCN(C)C)C)C(/N=C/C=5C(Cl)=C(Cl)N=CC5)=C4)=NC=C3

Molecular Formula

C33H36Cl2N8O2

Molecular Weight

647.597

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
GTR19258320-01	EGFR-IN-161
BA1597-100	WT-161
HY-172964	KIM-161
RFA77420-01	N 161
441888-01	ATN 161
MBS3845737-01	ATN-161
MBS3602418-01	CD 161
TRC-L270000-1G	LCL 161
GTR19222856-01	RC 161
GTR19249675-01	V-161

EGFR-IN-161

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